(−)-Kusunokinin as a Potential Aldose Reductase Inhibitor: Equivalency Observed via AKR1B1 Dynamics Simulation

[Image: see text] (−)-Kusunokinin performed its anticancer potency through CFS1R and AKT pathways. Its ambiguous binding target has, however, hindered the next development phase. Our study thus applied molecular docking and molecular dynamics simulation to predict the protein target from the pathway...

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Detalles Bibliográficos
Autores principales: Tanawattanasuntorn, Tanotnon, Thongpanchang, Tienthong, Rungrotmongkol, Thanyada, Hanpaibool, Chonnikan, Graidist, Potchanapond, Tipmanee, Varomyalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807751/
https://www.ncbi.nlm.nih.gov/pubmed/33458512
http://dx.doi.org/10.1021/acsomega.0c05102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807751/
https://www.ncbi.nlm.nih.gov/pubmed/33458512
http://dx.doi.org/10.1021/acsomega.0c05102

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