Current cancer driver variant predictors learn to recognize driver genes instead of functional variants

BACKGROUND: Identifying variants that drive tumor progression (driver variants) and distinguishing these from variants that are a byproduct of the uncontrolled cell growth in cancer (passenger variants) is a crucial step for understanding tumorigenesis and precision oncology. Various bioinformatics...

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Detalles Bibliográficos
Autores principales: Raimondi, Daniele, Passemiers, Antoine, Fariselli, Piero, Moreau, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807764/
https://www.ncbi.nlm.nih.gov/pubmed/33441128
http://dx.doi.org/10.1186/s12915-020-00930-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807764/
https://www.ncbi.nlm.nih.gov/pubmed/33441128
http://dx.doi.org/10.1186/s12915-020-00930-0

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