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Current cancer driver variant predictors learn to recognize driver genes instead of functional variants

BACKGROUND: Identifying variants that drive tumor progression (driver variants) and distinguishing these from variants that are a byproduct of the uncontrolled cell growth in cancer (passenger variants) is a crucial step for understanding tumorigenesis and precision oncology. Various bioinformatics...

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Detalles Bibliográficos
Autores principales:	Raimondi, Daniele, Passemiers, Antoine, Fariselli, Piero, Moreau, Yves
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807764/ https://www.ncbi.nlm.nih.gov/pubmed/33441128 http://dx.doi.org/10.1186/s12915-020-00930-0

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