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Mitigation of biases in estimating hazard ratios under non-sensitive and non-specific observation of outcomes–applications to influenza vaccine effectiveness

BACKGROUND: Non-sensitive and non-specific observation of outcomes in time-to-event data affects event counts as well as the risk sets, thus, biasing the estimation of hazard ratios. We investigate how imperfect observation of incident events affects the estimation of vaccine effectiveness based on...

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Detalles Bibliográficos
Autores principales: Baum, Ulrike, Kulathinal, Sangita, Auranen, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807790/
https://www.ncbi.nlm.nih.gov/pubmed/33446220
http://dx.doi.org/10.1186/s12982-020-00091-z