Cholesteryl-Conjugated Ribonuclease A Exhibits Enzyme Activity in Aqueous Solution and Resistance to Dimethyl Sulfoxide

[Image: see text] Using bovine pancreatic ribonuclease A (RNase A) and cholesterol, we synthesized cholesteryl-conjugated ribonuclease A (CHRNase A) to evaluate the influence of a conjugated hydrophobic moiety on protein function. Nuclear magnetic resonance and matrix-assisted laser desorption/ioniz...

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Detalles Bibliográficos
Autores principales: Katsura, Shinji, Furuishi, Takayuki, Ueda, Haruhisa, Yonemochi, Etsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807799/
https://www.ncbi.nlm.nih.gov/pubmed/33458505
http://dx.doi.org/10.1021/acsomega.0c05016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807799/
https://www.ncbi.nlm.nih.gov/pubmed/33458505
http://dx.doi.org/10.1021/acsomega.0c05016

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