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Cholesteryl-Conjugated Ribonuclease A Exhibits Enzyme Activity in Aqueous Solution and Resistance to Dimethyl Sulfoxide
[Image: see text] Using bovine pancreatic ribonuclease A (RNase A) and cholesterol, we synthesized cholesteryl-conjugated ribonuclease A (CHRNase A) to evaluate the influence of a conjugated hydrophobic moiety on protein function. Nuclear magnetic resonance and matrix-assisted laser desorption/ioniz...
Autores principales: | Katsura, Shinji, Furuishi, Takayuki, Ueda, Haruhisa, Yonemochi, Etsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807799/ https://www.ncbi.nlm.nih.gov/pubmed/33458505 http://dx.doi.org/10.1021/acsomega.0c05016 |
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