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In the presence of TGF-β1, Asperosaponin VI promotes human mesenchymal stem cell differentiation into nucleus pulposus like- cells

BACKGROUND: The regeneration of nucleus pulposus (NP) cells is an effective method to prevent intervertebral disc degeneration (IVDD). In this study, we investigated the role of Asperosaponin VI (ASA VI), isolated from a traditional Chinese medicine (TCM), the root of Dipsacus asper Wall, in promoti...

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Detalles Bibliográficos
Autores principales: Niu, Yong-tao, Xie, Lin, Deng, Rong-Rong, Zhang, Xiao-yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807821/
https://www.ncbi.nlm.nih.gov/pubmed/33446173
http://dx.doi.org/10.1186/s12906-020-03169-y