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Development of an engineered peptide antagonist against periostin to overcome doxorubicin resistance in breast cancer

BACKGROUND: Chemoresistance is one of the main problems in treatment of cancer. Periostin (PN) is a stromal protein which is mostly secreted from cancer associated fibroblasts in the tumor microenvironment and can promote cancer progression including cell survival, metastasis, and chemoresistance. T...

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Detalles Bibliográficos
Autores principales: Oo, Khine Kyaw, Kamolhan, Thanpawee, Soni, Anish, Thongchot, Suyanee, Mitrpant, Chalermchai, O-charoenrat, Pornchai, Thuwajit, Chanitra, Thuwajit, Peti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807878/
https://www.ncbi.nlm.nih.gov/pubmed/33446140
http://dx.doi.org/10.1186/s12885-020-07761-w