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Development of an engineered peptide antagonist against periostin to overcome doxorubicin resistance in breast cancer
BACKGROUND: Chemoresistance is one of the main problems in treatment of cancer. Periostin (PN) is a stromal protein which is mostly secreted from cancer associated fibroblasts in the tumor microenvironment and can promote cancer progression including cell survival, metastasis, and chemoresistance. T...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807878/ https://www.ncbi.nlm.nih.gov/pubmed/33446140 http://dx.doi.org/10.1186/s12885-020-07761-w |