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Analytical modeling of depth-dose degradation in heterogeneous lung tissue for intensity-modulated proton therapy planning

BACKGROUND AND PURPOSE: Proton therapy may be promising for treating non-small-cell lung cancer due to lower doses to the lung and heart, as compared to photon therapy. A reported challenge is degradation, i.e., a smoothing of the depth-dose distribution due to heterogeneous lung tissue. For pencil...

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Detalles Bibliográficos
Autores principales: Winter, Johanna, Ellerbrock, Malte, Jäkel, Oliver, Greilich, Steffen, Bangert, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807882/
https://www.ncbi.nlm.nih.gov/pubmed/33458311
http://dx.doi.org/10.1016/j.phro.2020.05.001