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A robust platform for expansion and genome editing of primary human natural killer cells

Genome editing is a powerful technique for delineating complex signaling circuitry and enhancing the functionality of immune cells for immunotherapy. Natural killer (NK) cells are potent immune effectors against cell malignancy, but they are challenging to modify genetically by conventional methods...

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Detalles Bibliográficos
Autores principales: Huang, Rih-Sheng, Lai, Min-Chi, Shih, Hsin-An, Lin, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808298/
https://www.ncbi.nlm.nih.gov/pubmed/33433623
http://dx.doi.org/10.1084/jem.20201529