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Rational selection of building blocks for the assembly of bispecific antibodies

Bispecific antibodies, engineered to recognize two targets simultaneously, demonstrate exceptional clinical potential for the therapeutic intervention of complex diseases. However, these molecules are often composed of multiple polypeptide chains of differing sequences. To meet industrial scale prod...

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Detalles Bibliográficos
Autores principales: Gong, Danyang, Riley, Timothy P., Bzymek, Krzysztof P., Correia, Ana R., Li, Danqing, Spahr, Christopher, Robinson, John H., Case, Ryan B., Wang, Zhulun, Garces, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808324/
https://www.ncbi.nlm.nih.gov/pubmed/33397191
http://dx.doi.org/10.1080/19420862.2020.1870058