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Rational selection of building blocks for the assembly of bispecific antibodies
Bispecific antibodies, engineered to recognize two targets simultaneously, demonstrate exceptional clinical potential for the therapeutic intervention of complex diseases. However, these molecules are often composed of multiple polypeptide chains of differing sequences. To meet industrial scale prod...
Autores principales: | Gong, Danyang, Riley, Timothy P., Bzymek, Krzysztof P., Correia, Ana R., Li, Danqing, Spahr, Christopher, Robinson, John H., Case, Ryan B., Wang, Zhulun, Garces, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808324/ https://www.ncbi.nlm.nih.gov/pubmed/33397191 http://dx.doi.org/10.1080/19420862.2020.1870058 |
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