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Sex-dependent role of microglia in disulfide high mobility group box 1 protein-mediated mechanical hypersensitivity

High mobility group box 1 protein (HMGB1) is increasingly regarded as an important player in the spinal regulation of chronic pain. Although it has been reported that HMGB1 induces spinal glial activation in a Toll-like receptor (TLR)4-dependent fashion, the aspect of sexual dimorphisms has not been...

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Detalles Bibliográficos
Autores principales: Agalave, Nilesh M., Rudjito, Resti, Farinotti, Alex Bersellini, Khoonsari, Payam Emami, Sandor, Katalin, Nomura, Yuki, Szabo-Pardi, Thomas A., Urbina, Carlos Morado, Palada, Vinko, Price, Theodore J., Erlandsson Harris, Helena, Burton, Michael D., Kultima, Kim, Svensson, Camilla I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808363/
https://www.ncbi.nlm.nih.gov/pubmed/32773600
http://dx.doi.org/10.1097/j.pain.0000000000002033