Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells

CONTEXT: Berberine (BBR) is used to treat diarrhoea and gastroenteritis in the clinic. It was found to have anticolon cancer effects. OBJECTIVE: To study the anticolon cancer mechanism of BBR by connectivity map (CMAP) analysis. MATERIALS AND METHODS: CMAP based mechanistic prediction was conducted...

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Detalles Bibliográficos
Autores principales: Li, Ge, Zhang, Chuang, Liang, Wei, Zhang, Yanbing, Shen, Yunheng, Tian, Xinhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808376/
https://www.ncbi.nlm.nih.gov/pubmed/33417512
http://dx.doi.org/10.1080/13880209.2020.1865407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808376/
https://www.ncbi.nlm.nih.gov/pubmed/33417512
http://dx.doi.org/10.1080/13880209.2020.1865407

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