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A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma

Immune checkpoint blockade (ICB) expands the therapeutic options for metastatic lung cancer nowadays representing a standard frontline strategy as monotherapy or combination therapy, as well as an option in oncogene-addicted NSCLC after exhaustion of targeted therapies. Predictive markers are urgent...

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Detalles Bibliográficos
Autores principales: Budczies, Jan, Kirchner, Martina, Kluck, Klaus, Kazdal, Daniel, Glade, Julia, Allgäuer, Michael, Kriegsmann, Mark, Heußel, Claus-Peter, Herth, Felix J., Winter, Hauke, Meister, Michael, Muley, Thomas, Fröhling, Stefan, Peters, Solange, Seliger, Barbara, Schirmacher, Peter, Thomas, Michael, Christopoulos, Petros, Stenzinger, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808386/
https://www.ncbi.nlm.nih.gov/pubmed/33520406
http://dx.doi.org/10.1080/2162402X.2020.1860586