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A “Build and Retrieve” methodology to simultaneously solve cryo-EM structures of membrane proteins
Single-particle cryo-electron microscopy (cryo-EM) has become a powerful technique in the field of structural biology. However, the inability to reliably produce pure, homogeneous membrane protein samples significantly hampers the progress of their structural determination. Here, we develop a bottom...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808410/ https://www.ncbi.nlm.nih.gov/pubmed/33408407 http://dx.doi.org/10.1038/s41592-020-01021-2 |