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Selective Targeting of Nav1.7 with Engineered Spider Venom-Based Peptides
A fundamental mechanism that drives the propagation of electrical signals in the nervous system is the activation of voltage-gated sodium channels. The sodium channel subtype Nav1.7 is critical for the transmission of pain-related signaling, with gain-of-function mutations in Nav1.7 resulting in var...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808416/ https://www.ncbi.nlm.nih.gov/pubmed/33427574 http://dx.doi.org/10.1080/19336950.2020.1860382 |