Post-translational knockdown and post-secretional modification of EsxA determine contribution of EsxA membrane permeabilizing activity for mycobacterial intracellular survival

Current genetic studies (e.g. gene knockout) have suggested that EsxA and EsxB function as secreted virulence factors that are essential for Mycobaterium tuberculosis (Mtb) intracellular survival, specifically in mediating phagosome rupture and translocation of Mtb to the cytosol of host cells, whic...

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Detalles Bibliográficos
Autores principales: Bao, Yanqing, Wang, Lin, Sun, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808419/
https://www.ncbi.nlm.nih.gov/pubmed/33356823
http://dx.doi.org/10.1080/21505594.2020.1867438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808419/
https://www.ncbi.nlm.nih.gov/pubmed/33356823
http://dx.doi.org/10.1080/21505594.2020.1867438

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