Changes in peripheral HCN2 channels during persistent inflammation

Nociceptor sensitization following nerve injury or inflammation leads to chronic pain. An increase in the nociceptor hyperpolarization-activated current, I(h), is observed in many models of pathological pain. Pharmacological blockade of I(h) prevents the mechanical and thermal hypersensitivity that...

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Detalles Bibliográficos
Autores principales: Jansen, L-A. R., Forster, L. A., Smith, X. L., Rubaharan, M., Murphy, A. Z., Baro, D. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808421/
https://www.ncbi.nlm.nih.gov/pubmed/33423595
http://dx.doi.org/10.1080/19336950.2020.1870086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808421/
https://www.ncbi.nlm.nih.gov/pubmed/33423595
http://dx.doi.org/10.1080/19336950.2020.1870086

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