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CLK-2/TEL2 is a conserved component of the nonsense-mediated mRNA decay pathway

Nonsense-mediated mRNA decay (NMD) controls eukaryotic mRNA quality, inducing the degradation of faulty transcripts. Key players in the NMD pathway were originally identified, through genetics, in Caenorhabditis elegans as smg (suppressor with morphological effect on genitalia) genes. Using forward...

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Detalles Bibliográficos
Autores principales: Guo, Yanwu, Tocchini, Cristina, Ciosk, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808604/
https://www.ncbi.nlm.nih.gov/pubmed/33444416
http://dx.doi.org/10.1371/journal.pone.0244505