PGE2 upregulates the Na(+)/K(+) ATPase in HepG2 cells via EP4 receptors and intracellular calcium

The Na(+)/K(+) ATPase is a key regulator of the hepatocytes ionic homeostasis, which when altered may lead to many liver disorders. We demonstrated recently, a significant stimulation of the Na(+)/K(+) ATPase in HepG2 cells treated with the S1P analogue FTY 720P, that was mediated through PGE2. The...

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Detalles Bibliográficos
Autores principales: Hodeify, Rawad, Chakkour, Mohamed, Rida, Reem, Kreydiyyeh, Sawsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808645/
https://www.ncbi.nlm.nih.gov/pubmed/33444342
http://dx.doi.org/10.1371/journal.pone.0245400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808645/
https://www.ncbi.nlm.nih.gov/pubmed/33444342
http://dx.doi.org/10.1371/journal.pone.0245400

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