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PGE2 upregulates the Na(+)/K(+) ATPase in HepG2 cells via EP4 receptors and intracellular calcium
The Na(+)/K(+) ATPase is a key regulator of the hepatocytes ionic homeostasis, which when altered may lead to many liver disorders. We demonstrated recently, a significant stimulation of the Na(+)/K(+) ATPase in HepG2 cells treated with the S1P analogue FTY 720P, that was mediated through PGE2. The...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808645/ https://www.ncbi.nlm.nih.gov/pubmed/33444342 http://dx.doi.org/10.1371/journal.pone.0245400 |