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The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease representing a serious unmet medical need. The disease is associated with the loss of self-tolerance and exaggerated B cell activation, resulting in autoantibody production and the formation of immune complexes that accumulate in the...

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Detalles Bibliográficos
Autores principales: Katewa, Arna, Suto, Eric, Hui, Jessica, Heredia, Jose, Liang, Jie, Hackney, Jason, Anderson, Keith, Alcantar, Tuija M., Bacarro, Natasha, Dunlap, Debra, Eastham, Jeffrey, Paler-Martinez, Andres, Rairdan, Xin Y., Modrusan, Zora, Lee, Wyne P., Austin, Cary D., Lafkas, Daniel, Ghilardi, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808665/
https://www.ncbi.nlm.nih.gov/pubmed/33444326
http://dx.doi.org/10.1371/journal.pone.0244439