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The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease representing a serious unmet medical need. The disease is associated with the loss of self-tolerance and exaggerated B cell activation, resulting in autoantibody production and the formation of immune complexes that accumulate in the...
Autores principales: | Katewa, Arna, Suto, Eric, Hui, Jessica, Heredia, Jose, Liang, Jie, Hackney, Jason, Anderson, Keith, Alcantar, Tuija M., Bacarro, Natasha, Dunlap, Debra, Eastham, Jeffrey, Paler-Martinez, Andres, Rairdan, Xin Y., Modrusan, Zora, Lee, Wyne P., Austin, Cary D., Lafkas, Daniel, Ghilardi, Nico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808665/ https://www.ncbi.nlm.nih.gov/pubmed/33444326 http://dx.doi.org/10.1371/journal.pone.0244439 |
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