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Cichoric Acid Ameliorates Monosodium Urate-Induced Inflammatory Response by Reducing NLRP3 Inflammasome Activation via Inhibition of NF-kB Signaling Pathway

Gouty arthritis is characterized by the deposition of monosodium urate (MSU) within synovial joints and tissues due to increased urate concentrations. Here, we elucidated the role of the natural compound cichoric acid (CA) on the MSU crystal-stimulated inflammatory response. The THP-1-derived macrop...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Lin, Bingfeng, Li, Zhifeng, Su, Jie, Feng, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808822/
https://www.ncbi.nlm.nih.gov/pubmed/33505510
http://dx.doi.org/10.1155/2021/8868527