Cargando…

Transcriptome analysis of iBET-151, a BET inhibitor alone and in combination with paclitaxel in gastric cancer cells

BET inhibitor, as an epigenetic regulator inhibitor, reduces the expression of oncogenes such as Myc and Bcl-2, which affects cancer growth and development. However, it has modest activity because of the narrow therapeutic index. Therefore, combination therapy is necessary to increase the anti-tumor...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Sun Kyoung, Bae, Hyun Joo, Kwon, Woo Sun, Che, Jingmin, Kim, Tae Soo, Chung, Hyun Cheol, Rha, Sun Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808866/
https://www.ncbi.nlm.nih.gov/pubmed/33412753
http://dx.doi.org/10.5808/GI.2020.18.4.e37