Cargando…

Epigenetic targeting of neuropilin-1 prevents bypass signaling in drug-resistant breast cancer

Human epidermal growth factor receptor 2 (HER2)-amplified breast cancers are treated using targeted antibodies and kinase inhibitors, but resistance to these therapies leads to systemic tumor recurrence of metastatic disease. Herein, we conducted gene expression analyses of HER2 kinase inhibitor-res...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdullah, Ammara, Akhand, Saeed Salehin, Paez, Juan Sebastian Paez, Brown, Wells, Pan, Li, Libring, Sarah, Badamy, Michael, Dykuizen, Emily, Solorio, Luis, Andy Tao, W., Wendt, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808937/
https://www.ncbi.nlm.nih.gov/pubmed/33128042
http://dx.doi.org/10.1038/s41388-020-01530-6