Epigenetic silencing of LncRNA LINC00261 promotes c-myc-mediated aerobic glycolysis by regulating miR-222-3p/HIPK2/ERK axis and sequestering IGF2BP1

Long noncoding RNAs have been identified as key regulators in the progression of various cancers. LINC00261 has been reported as a tumor suppressor in multiple cancers. However, its function and underlying mechanisms in pancreatic cancer remain largely unclear. Quantitative real-time PCR was perform...

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Detalles Bibliográficos
Autores principales: Zhai, Shuyu, Xu, Zhiwei, Xie, Junjie, Zhang, Jun, Wang, Xinjing, Peng, Chenghong, Li, Hongwei, Chen, Hao, Shen, Baiyong, Deng, Xiaxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808938/
https://www.ncbi.nlm.nih.gov/pubmed/33122827
http://dx.doi.org/10.1038/s41388-020-01525-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808938/
https://www.ncbi.nlm.nih.gov/pubmed/33122827
http://dx.doi.org/10.1038/s41388-020-01525-3

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