Fbxl8 suppresses lymphoma growth and hematopoietic transformation through degradation of cyclin D3

Overexpression of D-type cyclins in human cancer frequently occurs as a result of protein stabilization, emphasizing the importance of identification of the machinery that regulates their ubiqutin-dependent degradation. Cyclin D3 is overexpressed in ~50% of Burkitt’s lymphoma correlating with a muta...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshida, Akihiro, Choi, Jaewoo, Jin, Hong Ri, Li, Yan, Bajpai, Sagar, Qie, Shuo, Diehl, J. Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808939/
https://www.ncbi.nlm.nih.gov/pubmed/33122824
http://dx.doi.org/10.1038/s41388-020-01532-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808939/
https://www.ncbi.nlm.nih.gov/pubmed/33122824
http://dx.doi.org/10.1038/s41388-020-01532-4

Ejemplares similares