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Fbxl8 suppresses lymphoma growth and hematopoietic transformation through degradation of cyclin D3

Overexpression of D-type cyclins in human cancer frequently occurs as a result of protein stabilization, emphasizing the importance of identification of the machinery that regulates their ubiqutin-dependent degradation. Cyclin D3 is overexpressed in ~50% of Burkitt’s lymphoma correlating with a muta...

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Detalles Bibliográficos
Autores principales:	Yoshida, Akihiro, Choi, Jaewoo, Jin, Hong Ri, Li, Yan, Bajpai, Sagar, Qie, Shuo, Diehl, J. Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7808939/ https://www.ncbi.nlm.nih.gov/pubmed/33122824 http://dx.doi.org/10.1038/s41388-020-01532-4

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