Androgen receptor and its splice variant, AR-V7, differentially induce mRNA splicing in prostate cancer cells

Prostate cancer (PCa) is dependent on the androgen receptor (AR). Advanced PCa is treated with an androgen deprivation therapy-based regimen; tumors develop resistance, although they typically remain AR-dependent. Expression of constitutively active AR variants lacking the ligand-binding domain incl...

Descripción completa

Detalles Bibliográficos
Autores principales: Rana, Manjul, Dong, Jianrong, Robertson, Matthew J., Basil, Paul, Coarfa, Cristian, Weigel, Nancy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809134/
https://www.ncbi.nlm.nih.gov/pubmed/33446905
http://dx.doi.org/10.1038/s41598-021-81164-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809134/
https://www.ncbi.nlm.nih.gov/pubmed/33446905
http://dx.doi.org/10.1038/s41598-021-81164-0

Ejemplares similares