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Androgen receptor and its splice variant, AR-V7, differentially induce mRNA splicing in prostate cancer cells
Prostate cancer (PCa) is dependent on the androgen receptor (AR). Advanced PCa is treated with an androgen deprivation therapy-based regimen; tumors develop resistance, although they typically remain AR-dependent. Expression of constitutively active AR variants lacking the ligand-binding domain incl...
Autores principales: | Rana, Manjul, Dong, Jianrong, Robertson, Matthew J., Basil, Paul, Coarfa, Cristian, Weigel, Nancy L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809134/ https://www.ncbi.nlm.nih.gov/pubmed/33446905 http://dx.doi.org/10.1038/s41598-021-81164-0 |
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