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Icariin attenuates endothelial-mesenchymal transition via H19/miR-148b-3p/ELF5 in ox-LDL-stimulated HUVECs

Atherosclerosis is the main cause of cardio-cerebrovascular diseases. Endothelial-mesenchymal transition plays an important role in atherosclerosis. Icariin has a protective effect on atherosclerosis; however, the underlying mechanism remains unclear. In this study, we explored the molecular mechani...

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Detalles Bibliográficos
Autores principales: Liu, Shan, Xu, Dong-sheng, Li, Min, Zhang, Yang, Li, Qi, Li, Teng-teng, Ren, Li-qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809175/
https://www.ncbi.nlm.nih.gov/pubmed/33510936
http://dx.doi.org/10.1016/j.omtn.2020.11.021