A study of the dopamine transporter using the TRACT assay, a novel in vitro tool for solute carrier drug discovery

Members of the solute carrier (SLC) transporter protein family are increasingly recognized as therapeutic drug targets. The majority of drug screening assays for SLCs are based on the uptake of radiolabeled or fluorescent substrates. Thus, these approaches often have limitations that compromise on t...

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Detalles Bibliográficos
Autores principales: Sijben, Hubert J., van den Berg, Julie J. E., Broekhuis, Jeremy D., IJzerman, Adriaan P., Heitman, Laura H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809260/
https://www.ncbi.nlm.nih.gov/pubmed/33446713
http://dx.doi.org/10.1038/s41598-020-79218-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809260/
https://www.ncbi.nlm.nih.gov/pubmed/33446713
http://dx.doi.org/10.1038/s41598-020-79218-w

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