A mathematical model of tumor regression and recurrence after therapeutic oncogene inactivation

The targeted inactivation of individual oncogenes can elicit regression of cancers through a phenomenon called oncogene addiction. Oncogene addiction is mediated by cell-autonomous and immune-dependent mechanisms. Therapeutic resistance to oncogene inactivation leads to recurrence but can be counter...

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Detalles Bibliográficos
Autores principales: Hori, Sharon S., Tong, Ling, Swaminathan, Srividya, Liebersbach, Mariola, Wang, Jingjing, Gambhir, Sanjiv S., Felsher, Dean W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809285/
https://www.ncbi.nlm.nih.gov/pubmed/33446671
http://dx.doi.org/10.1038/s41598-020-78947-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809285/
https://www.ncbi.nlm.nih.gov/pubmed/33446671
http://dx.doi.org/10.1038/s41598-020-78947-2

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