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Changes on proteomic and metabolomic profile in serum of mice induced by chronic exposure to tramadol
Tramadol is an opioid used as an analgesic for treating moderate or severe pain. The long-term use of tramadol can induce several adverse effects. The toxicological mechanism of tramadol abuse is unclear. Limited literature available indicates the change of proteomic profile after chronic exposure t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809287/ https://www.ncbi.nlm.nih.gov/pubmed/33446901 http://dx.doi.org/10.1038/s41598-021-81109-7 |