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Changes on proteomic and metabolomic profile in serum of mice induced by chronic exposure to tramadol

Tramadol is an opioid used as an analgesic for treating moderate or severe pain. The long-term use of tramadol can induce several adverse effects. The toxicological mechanism of tramadol abuse is unclear. Limited literature available indicates the change of proteomic profile after chronic exposure t...

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Detalles Bibliográficos
Autores principales: Jiang, Shukun, Liu, Guojie, Yuan, Huiya, Xu, Enyu, Xia, Wei, Zhang, Xiaoyu, Liu, Junting, Gao, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809287/
https://www.ncbi.nlm.nih.gov/pubmed/33446901
http://dx.doi.org/10.1038/s41598-021-81109-7