Positive-charge tuned gelatin hydrogel-siSPARC injectable for siRNA anti-scarring therapy in post glaucoma filtration surgery

Small interfering RNA (siRNA) therapy is a promising epigenetic silencing strategy. However, its widespread adoption has been severely impeded by its ineffective delivery into the cellular environment. Here, a biocompatible injectable gelatin-based hydrogel with positive-charge tuned surface charge...

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Detalles Bibliográficos
Autores principales: Chun, Yong Yao, Yap, Zhu Li, Seet, Li Fong, Chan, Hiok Hong, Toh, Li Zhen, Chu, Stephanie W. L., Lee, Ying Shi, Wong, Tina T., Tan, Timothy T. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809290/
https://www.ncbi.nlm.nih.gov/pubmed/33446775
http://dx.doi.org/10.1038/s41598-020-80542-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809290/
https://www.ncbi.nlm.nih.gov/pubmed/33446775
http://dx.doi.org/10.1038/s41598-020-80542-4

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