NT-PGC-1α deficiency attenuates high-fat diet-induced obesity by modulating food intake, fecal fat excretion and intestinal fat absorption

Transcriptional coactivator PGC-1α and its splice variant NT-PGC-1α regulate metabolic adaptation by modulating many gene programs. Selective ablation of PGC-1α attenuates diet-induced obesity through enhancing fatty acid oxidation and thermogenesis by upregulation of NT-PGC-1α in brown adipose tiss...

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Detalles Bibliográficos
Autores principales: Kim, Jihyun, Moon, Jiyoung, Park, Chul-Hong, Lee, Jisu, Cheng, Helia, Floyd, Z. Elizabeth, Chang, Ji Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809341/
https://www.ncbi.nlm.nih.gov/pubmed/33446719
http://dx.doi.org/10.1038/s41598-020-79823-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809341/
https://www.ncbi.nlm.nih.gov/pubmed/33446719
http://dx.doi.org/10.1038/s41598-020-79823-9

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