Dermal fibroblasts cultured from donors with type 2 diabetes mellitus retain an epigenetic memory associated with poor wound healing responses

The prevalence of Type 2 diabetes mellitus (T2DM) is escalating globally. Patients suffer from multiple complications including the development of chronic wounds that can lead to amputation. These wounds are characterised by an inflammatory environment including elevated tumour necrosis factor alpha...

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Detalles Bibliográficos
Autores principales: Al-Rikabi, Aaiad H. A., Tobin, Desmond J., Riches-Suman, Kirsten, Thornton, M. Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809350/
https://www.ncbi.nlm.nih.gov/pubmed/33446687
http://dx.doi.org/10.1038/s41598-020-80072-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809350/
https://www.ncbi.nlm.nih.gov/pubmed/33446687
http://dx.doi.org/10.1038/s41598-020-80072-z

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