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Single-neuron dynamical effects of dendritic pruning implicated in aging and neurodegeneration: towards a measure of neuronal reserve

Aging is a main risk factor for neurodegenerative disorders including Alzheimer's disease. It is often accompanied by reduced cognitive functions, gray-matter volume, and dendritic integrity. Although age-related brain structural changes have been observed across multiple scales, their function...

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Detalles Bibliográficos
Autores principales: Kirch, Christoph, Gollo, Leonardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809359/
https://www.ncbi.nlm.nih.gov/pubmed/33446683
http://dx.doi.org/10.1038/s41598-020-78815-z