ARNT deficiency represses pyruvate dehydrogenase kinase 1 to trigger ROS production and melanoma metastasis

The metabolic changes in melanoma cells that are required for tumor metastasis have not been fully elucidated. In this study, we show that the increase in glucose uptake and mitochondrial oxidative phosphorylation confers metastatic ability as a result of aryl hydrocarbon receptor nuclear translocat...

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Detalles Bibliográficos
Autores principales: Huang, Chi-Ruei, Chang, Ting-Wei, Lee, Chung-Ta, Shen, Chih-Jie, Chang, Wen-Chang, Chen, Ben-Kuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809415/
https://www.ncbi.nlm.nih.gov/pubmed/33446631
http://dx.doi.org/10.1038/s41389-020-00299-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809415/
https://www.ncbi.nlm.nih.gov/pubmed/33446631
http://dx.doi.org/10.1038/s41389-020-00299-3

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