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Effect of 5-HT2A receptor antagonism on levels of D2/3 receptor occupancy and adverse behavioral side-effects induced by haloperidol: a SPECT imaging study in the rat
Several studies suggested that 5-HT(2A) receptor (5-HT(2A)R) blockade may provide a more favorable efficacy and side-effect profile to antipsychotic treatment. We hypothesized that a combined haloperidol (a D(2/3) receptor (D(2/3)R) antagonist) and MDL-100,907 (a 5-HT(2A)R antagonist) treatment woul...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809418/ https://www.ncbi.nlm.nih.gov/pubmed/33446643 http://dx.doi.org/10.1038/s41398-020-01179-5 |