Complexity of the eukaryotic dolichol-linked oligosaccharide scramblase suggested by activity correlation profiling mass spectrometry

The oligosaccharide required for asparagine (N)-linked glycosylation of proteins in the endoplasmic reticulum (ER) is donated by the glycolipid Glc(3)Man(9)GlcNAc(2)-PP-dolichol. Remarkably, whereas glycosylation occurs in the ER lumen, the initial steps of Glc(3)Man(9)GlcNAc(2)-PP-dolichol synthesi...

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Detalles Bibliográficos
Autores principales: Verchère, Alice, Cowton, Andrew, Jenni, Aurelio, Rauch, Monika, Häner, Robert, Graumann, Johannes, Bütikofer, Peter, Menon, Anant K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809446/
https://www.ncbi.nlm.nih.gov/pubmed/33446867
http://dx.doi.org/10.1038/s41598-020-80956-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809446/
https://www.ncbi.nlm.nih.gov/pubmed/33446867
http://dx.doi.org/10.1038/s41598-020-80956-0

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