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Complexity of the eukaryotic dolichol-linked oligosaccharide scramblase suggested by activity correlation profiling mass spectrometry
The oligosaccharide required for asparagine (N)-linked glycosylation of proteins in the endoplasmic reticulum (ER) is donated by the glycolipid Glc(3)Man(9)GlcNAc(2)-PP-dolichol. Remarkably, whereas glycosylation occurs in the ER lumen, the initial steps of Glc(3)Man(9)GlcNAc(2)-PP-dolichol synthesi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809446/ https://www.ncbi.nlm.nih.gov/pubmed/33446867 http://dx.doi.org/10.1038/s41598-020-80956-0 |