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Ultra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function
TLR4 location, and bacterial species-derived lipopolysaccharides, play a significant role in the downstream activation of transcription factors, accessory molecules, and products. Here, this is demonstrated through the use of classically-activated and alternatively-activated macrophages. We show tha...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809447/ https://www.ncbi.nlm.nih.gov/pubmed/33446670 http://dx.doi.org/10.1038/s41598-020-79145-w |