HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow

Normal growth and development of lymphatic structures depends on mechanical forces created by accumulating interstitial fluid. However, prolonged exposure to pathologic mechanical stimuli generated by chronically elevated lymph flow results in lymphatic dysfunction. The mechanisms that transduce the...

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Detalles Bibliográficos
Autores principales: Boehme, Jason T., Morris, Catherine J., Chiacchia, Samuel R., Gong, Wenhui, Wu, Katherine Y., Kameny, Rebecca J., Raff, Gary W., Fineman, Jeffrey R., Maltepe, Emin, Datar, Sanjeev A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809484/
https://www.ncbi.nlm.nih.gov/pubmed/33446832
http://dx.doi.org/10.1038/s41598-020-80882-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809484/
https://www.ncbi.nlm.nih.gov/pubmed/33446832
http://dx.doi.org/10.1038/s41598-020-80882-1

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