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A nanoluciferase biosensor to investigate endogenous chemokine secretion and receptor binding

Secreted chemokines are critical mediators of cellular communication that elicit intracellular signaling by binding membrane-bound receptors. Here we demonstrate the development and use of a sensitive real-time approach to quantify secretion and receptor binding of native chemokines in live cells to...

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Detalles Bibliográficos
Autores principales: White, Carl W., Kilpatrick, Laura E., Pfleger, Kevin D.G., Hill, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809502/
https://www.ncbi.nlm.nih.gov/pubmed/33490919
http://dx.doi.org/10.1016/j.isci.2020.102011