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A nanoluciferase biosensor to investigate endogenous chemokine secretion and receptor binding
Secreted chemokines are critical mediators of cellular communication that elicit intracellular signaling by binding membrane-bound receptors. Here we demonstrate the development and use of a sensitive real-time approach to quantify secretion and receptor binding of native chemokines in live cells to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809502/ https://www.ncbi.nlm.nih.gov/pubmed/33490919 http://dx.doi.org/10.1016/j.isci.2020.102011 |