Sequence and Structure-Based Analysis of Specificity Determinants in Eukaryotic Protein Kinases

Protein kinases lie at the heart of cell-signaling processes and are often mutated in disease. Kinase target recognition at the active site is in part determined by a few amino acids around the phosphoacceptor residue. However, relatively little is known about how most preferences are encoded in the...

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Detalles Bibliográficos
Autores principales: Bradley, David, Viéitez, Cristina, Rajeeve, Vinothini, Selkrig, Joel, Cutillas, Pedro R., Beltrao, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809594/
https://www.ncbi.nlm.nih.gov/pubmed/33440154
http://dx.doi.org/10.1016/j.celrep.2020.108602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809594/
https://www.ncbi.nlm.nih.gov/pubmed/33440154
http://dx.doi.org/10.1016/j.celrep.2020.108602

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