Evidence for S2 flexibility by direct visualization of quantum dot–labeled myosin heads and rods within smooth muscle myosin filaments moving on actin in vitro

Myosins in muscle assemble into filaments by interactions between the C-terminal light meromyosin (LMM) subdomains of the coiled-coil rod domain. The two head domains are connected to LMM by the subfragment-2 (S2) subdomain of the rod. Our mixed kinetic model predicts that the flexibility and length...

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Detalles Bibliográficos
Autores principales: Brizendine, Richard K., Anuganti, Murali, Cremo, Christine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809879/
https://www.ncbi.nlm.nih.gov/pubmed/33439241
http://dx.doi.org/10.1085/jgp.202012751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809879/
https://www.ncbi.nlm.nih.gov/pubmed/33439241
http://dx.doi.org/10.1085/jgp.202012751

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