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Melatonin inhibits proliferation and viability and promotes apoptosis in colorectal cancer cells via upregulation of the microRNA-34a/449a cluster

Colorectal cancer (CRC) has a significant burden on healthcare systems worldwide, and is associated with high morbidity and mortality rates in patients. In 2020, the estimated new cases of colon cancer in the United States are 78,300 in men and 69,650 in women. Thus, developing effective and novel a...

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Detalles Bibliográficos
Autores principales: Ji, Guangyu, Zhou, Wenjuan, Li, Xian, Du, Jingyi, Li, Xinyue, Hao, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7809902/
https://www.ncbi.nlm.nih.gov/pubmed/33398374
http://dx.doi.org/10.3892/mmr.2021.11826